Relationship between left atrial appendage emptying velocity and the risk of ischemic stroke after catheter ablation in patients with persistent atrial fibrillation
Cui Jing
He Liu
Guo Qi
Guo Xueyuan
Li Songnan
Liu Nian
Huang Lihong
Dong Jianzeng
Ma Changsheng
Abstract：Objective To investigate the relationship between left atrial appendage emptying velocity(LAAeV)and the risk of ischemic stroke after catheter ablation in patients with persistent atrial fibrillation.Methods Patients with persistent atrial fibrillation who underwent ablation for the first time in Beijing Anzhen Hospital,Capital Medical University from March 2017 to December 2019 were retrospectively enrolled.The clinical and echocardiographic characteristics of the patients were collected.LAAeV was measured by transesophageal echocardiography before operation.Patients were followed up regularly to observe the primary outcome of ischemic stroke.Results A total of 926 patients were enrolled,and LAAeV was(40.1±18.3)cm/s.During a median follow-up of3.0(2.5,3.5)years,28 patients had ischemic stroke.Univariate analysis showed that previous ischemic stroke history(hazard ratio=2.925,95％confidence interval:1.323-6.465,P=0.008),left atrial anteroposterior diameter(hazard ratio=1.092,95％confidence interval:1.016-1.174,P=0.017),and LAAeV(hazard ratio=0.976,95％confidence interval:0.951-1.001,P=0.063)were associated with the incidence of ischemic stroke after atrial fibrillation ablation.Multivariate analysis showed that only the previous history of ischemic stroke(hazard ratio=2.494,95％confidence interval:1.085-5.734,P=0.031)was significantly related to the incidence of ischemic stroke after atrial fibrillation ablation.Conclusions The risk of ischemic stroke after catheter ablation in patients with persistent atrial fibrillation is related to previous ischemic stroke history.There is no significant correlation between the LAAeV and the risk of ischemic stroke in patients after catheter ablation.
Keywords：Atrial fibrillationCatheter ablationLeft atrial appendage emptying velocityIschemic stroke
Publication Date：2025-04-18
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 481-485 )