Effect observation of moist exposed burn ointment combined with concentrated growth factor in the treatment of diabetic foot
Bin Xiaochang
Wen Yujie
Mo Zishao
Abstract：Objective To investigate the effect of moist exposed burn ointment combined with concentrated growth factor in the treatment of diabetic foot.Methods A total of 90 patients with diabetic foot admitted to Nanxishan Hospital of Guangxi Zhuang Autonomous Region from January 2022 to January 2024 were selected as the research objects.They were divided into control group 1,control group 2 and combined group by random number table method,with 30 cases in each group.On the basis of basic comprehensive treatment,the control group 1 was treated with moistexposed burn ointment,the control group 2 was treated with concentrated growth factor,and the combined group was treated with moistexposed burn ointment combined with concentrated growth factor.The clinical efficacy,wound healing indicators,growth factor levels,inflammatory factor levels,and treatment safety were compared among the three groups.Results The total effective rate of the combined group was higher than those of the control group 1 and the control group 2[93.3％(28/30)vs 73.3％(22/30),70.0％(21/30)](both P＜0.05).After treatment,the wound healing area of combined group was larger than those of control group 1 and control group 2,while the growth time of new granulation tissue,healing time,and treatment cost of combined group were shorter/lower than those of control group 1 and control group 2(all P＜0.05).After treatment,the levels of vascular endothelial growth factor,basic fibroblast growth factor and epidermal growth factor in the combined group were higher than those in the control group 1 and the control group 2,and the levels of high-sensitivity C-reactive protein,tumor necrosis factor-α and interleukin-6 in the combined group were lower than those in the control group 1 and the control group 2(all P＜0.05).There was no significant difference in the incidence of adverse reactions among the three groups(P＞0.05).Conclusion Moist exposed burn ointment combined with concentrated growth factors has a good effect in the treatment of diabetic foot,which can promote wound healing,reduce treatment cost,improve the level of growth factors,reduce the level of inflammatory factors,and has good safety.
Keywords：Diabetic footConcentrated growth factorMoist exposed burn ointmentInflammatory factors
Publication Date：2025-03-07
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 428-432 )