A case of fever and recurrent thrombocytopenia attributed to cirrhosis of primary biliary cholangitis with systemic lupus erythematosus
Zhao Dan
Guo Qiaoli
Ren Junjie
Zhao Junmei
Abstract：Primary biliary cholangitis can combine other immune system diseases,when the two diseases appear at the same time,easily to cause complicated complications.This paper reports a case of a 66-year-old female patient with primary biliary cholangitis in the stage of liver cirrhosis who was admitted to the hospital due to unexplained fever and recurrent thrombocytopenia.After excluding infection,tumor,drug and other causes,the final diagnosis was primary biliary cholangitis,systemic lupus erythematosus,infective endocarditis,and the diagnosis and treatment process was analyzed.On the basis of anti-infection treatment,the patient was given avatrobopag maleate to increase platelet.Systemic lupus erythematosus was treated with corticosteroids,cyclosporine and hydroxychloroquine,and the patient's condition improved and was discharged.Half a year later,no aortic valve vegetation was found by echocardiography in the outpatient follow-up,which was good for clinical reference.
Keywords：Primary biliary cholangitisSystemic lupus erythematosusFeverThrombocytopenia
Publication Date：2025-02-07
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 285-287 )