Analysis of drug research progress in chronic hepatitis B cirrhosis
Zhong Min
Wang Xiaoze
Yang Xiaoli
Abstract：Chronic hepatitis B is a global epidemic disease.It is caused by hepatitis B virus infection and can develop into liver disease at different stages such as cirrhosis,liver failure,and hepatocellular carcinoma.At present,chronic hepatitis B cirrhosis is mainly treated with antiviral therapy,combined with immunotherapy and liver protective therapy.Antiviral drugs can inhibit virus replication and alleviate disease progression.Liver protec-tive therapy mainly reduces liver injury by anti-oxidation,anti-inflamumation and promoting hepatocyte regenera-tion.Emerging therapeutic approaches such as gene editing technology,immunotherapy drugs,immune agents combined with antiviral drugs,and RNA interference therapy have also shown great potential in pre-clinical and clinical studies.In this paper,the current research progress of drugs for chronic hepatitis B cirrhosis is summa-rized,and the research progress,mechanism and clinical application prospect of these treatment methods are discussed in detail.
Keywords：Chronic hepatitis B cirrhosisDrug treatmentAnalysis of current situation
Publication Date：2024-11-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1737-1741 )