Study on the clinical effect of acupuncture Xingshen four points combined with cognitive-motor dual task training in the treatment of cerebral infarction complicated with cognitive dysfunction

Chen Jun; Chen Ruimei; Li Donghe; Li Xuecha

doi:10.3760/j.issn.1673-4777.2024.10.018

Abstract：Objective To explore the clinical effect of acupuncture Xingshen four points combined with cognitive-motor dual task training(CMDT)in the treatment of cerebral infarction complicated with cognitive dysfunction.Methods A total of 96 patients with cerebral infarction combined with cognitive dysfunction admitted to the Second Affiliated Hospital of Hainan Medical College from August 2020 to August 2023 were selected and divided into control group and observation group by random number table method,with 48 cases in each group.On the basis of basic treatment,the control group was treated with CMDT for 4 weeks,and the observation group was treated with acupuncture Xingshen four points combined with CMDT for 4 weeks.The Montreal cognitive assess-ment(MoCA)score,Mini-mental state examination(MMSE)score,P300 amplitude and latency,national institutes of health stroke scale(NIHSS)score,neurotransmitter level and quality of life were compared between the two groups.Results After treatment,the MoCA and MMSE scores of the two groups were higher than those before treatment,and those of the observation group were higher than those of the control group(all P＜0.001).The P300 latencies of the two groups were shorter than those before treatment,and the observation group was shorter than that of the control group;the P300 amplitudes of the two groups were higher than those before treatment,and the observation group was higher than that of the control group(all P＜0.05).After treatment,the NIHSS scores of the two groups were lower than those before treatment,and the NIHSS score of the observation group was lower than that of the control group[(7.1±2.0)vs(10.3±2.6)](t=6.666,P＜0.001).The levels of serum acetylcholine and dopamine in the two groups were higher than those before treatment,and those in the observation group were higher than those in the control group(all P＜0.05).After treatment,the activities of daily living scale scores of the two groups were higher than those before treatment,and the observation group was higher than the control group[(60±15)vs(53±13)](t=2.569,P=0.012).Conclusion Acupuncture Xingshen four points combined with CMDT can effectively correct neurotransmitter disorder,improve cognitive function and neurological function,and improve the quality of life in patients with cerebral infarction and cognitive impairment.