The clinical effect of enhanced external counterpulsation in the treatment of angina pectoris with cardiac insufficiency and its influence on serum N-terminal pro-brain natriuretic peptide level
Wu Xianfeng
Xie Bei
Abstract：Objective To investigate the clinical effect of enhanced external counterpulsation in the treatment of angina pectoris with cardiac insufficiency and its influence on serum N-terminal pro-brain natriuretic peptide(NT-proBNP)level.Methods A total of 82 patients with angina pectoris and cardiac insufficiency who were diagnosed and treated in the People's Hospital of Jingmen,Hubei Province from April 2022 to April 2023 were selected as the research objects.According to the random number table method,they were divided into observation group and control group,with 41 cases in each group.The control group was given conventional drug treatment.The observation group was treated with enhanced external counterpulsation on the basis of the control group.The grading of angina pectoris,cardiac function indicators[left ventricular ejection fraction(LVEF),left ventricular fractional shortening(LVFS),left ventricular end diastolic diameter(LVEDD)],laboratory testing indicators[NT-proBNP,high-sensitivity C-reactive protein(hs-CRP),human galactose agglutinin 3(Galectin-3)]before and after treatment,and incidence of cardiovascular adverse events between two groups were compared.Results After treatment,the classification of angina pectoris in the observation group was better than that in the control group(Z=-6.933,P＜0.001).After treatment,LVEF of the two groups were higher than those before treatment,LVFS and LVEDD were lower than those before treatment,LVEF of the observation group was higher than that of the control group,LVFS and LVEDD were lower than those of the control group(all P＜0.05).After treatment,the NT-proBNP,hs-CRP,and Galectin-3 levels in both groups were lower than those before treatment,and those in the observation group were lower than those in the control group(all P＜0.05).The incidence of adverse cardiovascular events in the observation group was lower than that in the control group[4.9％(2/41)vs 22.0％(9/41)](P=0.023).Conclusion The effect of enhanced external counterpulsation in the treatment of patients with angina pectoris and cardiac insufficiency is significant,which can effectively improve the symptoms of angina pectoris and cardiac function,and reduce the levels of NT-proBNP and inflammatory factors.
Keywords：Angina pectorisCardiac insufficiencyEnhanced external counterpulsationN-terminal pro-brain natriuretic peptide
Publication Date：2024-09-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1299-1303 )