Perioperative characteristics of blink reflex in patients with primary trigeminal neuralgia undergoing percutaneous trigeminal gasserian ganglion balloon compression and its relationship with long-term postop-erative efficacy
Shi Haowei
Guo Wenchang
Wang Yinzhan
Wang Yongyu
Yang Sihui
Li Yang
Qian Tao
Abstract：Objective To investigate the perioperative characteristics of blink reflex in patients with primary trigeminal neuralgia(PTN)undergoing percutaneous trigeminal gasserian ganglion balloon compression(PBC)and its relationship with long-term postoperative efficacy.Methods The clinical data of 150 PTN patients who underwent PBC in Hebei General Hospital from February to October 2020 were collected and retrospectively analyzed.All patients were evaluated for facial numbness and pain using the Barrow Neurological Institute painse-verity(BNI-P)and Barrow Neurological Institute facial numbness(BNI-N)at 1 d before surgery,1 d after surgery,and 1,3,6,and 12 months after surgery,respectively.Blink reflex testing(involving the latency and amplitude of conduction pathways R1,R2,and R2')was also performed.According to the follow-up results in the third year after surgery,the patients were divided into cure group(120 cases)and recurrence group(30 cases).The clinical data of the two groups were compared,and the Logistic regression method was used to analyze the influencing factors of the long-term prognosis of the patients,establish a prediction model,and evaluate the goodness of fit of the model.Results The BNI-P scores of patients at 1 d after surgery and at 1,3,6,and 12 months after surgery were significantly lower than that at 1 d before surgery(all P＜0.05).After PBC treatment,the latency of R1,R2,and R2'showed an overall decreasing trend,while the amplitude of R1,R2,and R2'showed an overall increasing trend(all P＜0.05).The results of the multivariate Logistic regression analysis incorporating the most comprehensive factors showed that body mass index(odds ratio=1.254,P=0.028),disease duration(odds ratio=1.072,P=0.008),preoperative BNI-P(odds ratio=2.189,P=0.040),preoperative R1,R2,and R2'latency(odds ratio=3.546,4.165,1.314;P=0.012,0.014,0.038),and preoperative R1,R2,and R2'amplitude(odds ratio=0.933,0.920,0.942;P=0.009,0.003,0.002)were all influencing factors for long-term prognosis.The Hosmer-Lemeshow test showed that the model had good goodness of fit(P=0.796).Conclusions PBC treatment of PTN patients can achieve good clinical efficacy,and the blink reflex indexes show a decreasing trend with the follow-up time,and there is a positive correlation between the symptoms of facial numbness.Individual factors,preoperative levels of BNI-P and blink reflex have important effects on the long-term efficacy of PTN patients after surgery.
Keywords：Primary trigeminal neuralgiaPercutaneous trigeminal gasserian ganglion balloon compressionBlink reflexLong-term efficacy
Publication Date：2024-08-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1173-1177 )