Application effect observation of in-line mechanical insufflation-exsufflation technology in patients with invasive mechanical ventilation after cardiac surgery

Han Dannuo; Hou Dengbang; Du Zhongtao; Wang Liangshan; Jia Ming

doi:10.3760/j.issn.1673-4777.2024.06.005

Abstract：Objective To observe the clinical effect of in-line mechanical insufflation-exsufflation(IL-MIE)technology in airway secretion management of patients with invasive mechanical ventilation after cardiac surgery.Methods A total of 65 patients with invasive mechanical ventilation after cardiac surgery with cardiopulmonary bypass in the Cardiac Surgical Intensive Care Unit,Beijing Anzhen Hospital,Capital Medical University from July 2015 to July 2020 were retrospectively selected.Among them,33 patients treated with conventional catheter suction(CS)were selected as the control group,and 32 patients treated with automated IL-MIE equipment on the basis of conventional CS treatment were selected as the observation group.The general data,respiratory and circulatory related indicators during treatment,clinical and prognostic related indicators of the two groups were compared.Results There were no significant differences in general data between the two groups(all P＞0.05).At 0 h after treatment,the heart rate of the observation group was lower than that of the control group;at 4 and 8 h after treatment,the arterial partial pressure of oxygen,oxygenation index and static compliance in the observation group were higher than those in the control group,and the airway plateau pressure and heart rate were lower than those in the control group(all P＜0.05).The number of CS treatment and the duration of mechanical ventilation in the observation group were less/shorter than those in the control group[0(0,0)time vs 3(1,4)times,20(17,22)h vs 24(19,26)h,Z=-7.081,-2.067,both P＜0.05].Conclusion IL-MIE can improve oxygenation index and airway compliance,reduce the duration of mechanical ventilation and maintain hemodynamic stability during airway management in patients after cardiac surgery by simulating physiological airway clearance.