Research progress on the application of phosphodiesterase 4 inhibitors in dermatosis
Peng Xinxin
Niu Xuping
Abstract：Phosphodiesterase 4 is the main enzyme that metabolizes cyclic adenosine monophosphate in inflammatory cells and plays a crucial role in regulating the balance of second messengers.As the key signal transduction regulation factor,phosphodiesterase 4 in a variety of diseases shows a promising pharmacological target,the inhibitors have been used as a treatment drug.This article reviews the mechanism,efficacy and adverse reactions of phosphodiesterase 4 inhibitors in the treatment of dermatosis.
Keywords：DermatosisPhosphodiesterase 4Inflammatory factors
Publication Date：2024-05-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 792-796 )