Research progress on risk factors of in-stent restenosis in patients with coronary atherosclerotic heart disease and diabetes mellitus after percutaneous coronary intervention
Luo Hongchi
Ma Hanying
Han Hongya
Li Yadong
Liu Xiaoli
Zhao Tiefu
Abstract：The rate of in-stent restenosis in patients with coronary atherosclerotic heart disease and diabetes mellitus is significantly higher than that in patients without diabetes mellitus.It is characterized by abnormal glucose metabolism,blood glucose fluctuation,insulin resistance as the core,and is often accompanied by hyperlipidemia,hyperuricemia,abnormal coagulation and fibrinolysis indicators,chronic inflammation,etc.These factors directly or indirectly affect vascular endothelial function,promote smooth muscle proliferation,abnormal coagulation,and ultimately lead to the occurrence of restenosis.This review mainly summarizes and discusses the research on the risk factors of in-stent restenosis after percutaneous coronary intervention in patients with diabetes mellitus and coronary atherosclerotic heart disease,in order to provide a reference for reducing the incidence of in-stent restenosis and preventing the occurrence of adverse cardiovascular events.
Keywords：Coronary atherosclerotic heart diseaseDiabetes mellitusIn-stent restenosisPercuta-neous coronary interventionRisk factors
Publication Date：2024-05-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 763-767 )