Application of new double-tube laryngeal mask airway in the treatment of esophageal and gastric varices sclerotherapy combined with tissue glue injection in patients with liver cirrhosis

Zhao Jinying; Niu Shaoning; Li Ping; Zhang Ai; Cai Xiaofei; Cheng Hao

doi:10.3760/j.issn.1673-4777.2024.05.015

Abstract：Objective To investigate the efficacy and safety of new double-tube laryngeal mask airway in the treatment of esophageal and gastric varices sclerotherapy combined with tissue glue injection in patients with liver cirrhosis.Methods A prospective study was conducted on 80 patients with liver cirrhosis who were treated with esophagogastric varices sclerotherapy combined with tissue glue injection under gastroscopy in Beijing Ditan Hospital,Capital Medical University from August 2021 to July 2023.The patients were divided into observation group and control group by random number table method,with 40 cases in each group.The control group was given oxygen inhalation with the mask after the mouth opener placement,and the observation group was given oxygen inhalation with the new double-tube laryngeal mask inserted and connected with the breathing tube.The mean arterial pressure(MAP),heart rate,pulse oxygen saturation(SpO2),and bispectral index(BIS)were recorded and compared before anesthesia(T1),after laryngeal mask/bite placement(T2),5 min after placement(T3)and at the time of exit from the endoscope(T4).The incidence of adverse reactions and postoperative satisfaction of patients and doctors were compared between the two groups.Results There were no statistically significant differences in age,gender,body mass index,American Society of Anesthesiologists classification,operation time,anesthesia time,and propofol dosage between the two groups(all P＞0.05).There were no significant differences in MAP,heart rate and BIS value between the two groups at each time point(all P＞0.05).At T2,T3,and T4 time points,the SpO2 in the observation group were higher than those in the control group[(96.6±2.4)％vs(94.3±3.3)％,(97.1±2.1)％vs(92.2±3.9)％,(96.1±1.5)％vs(95.3±1.9)％](all P＜0.05).The incidence of hypoxemia in the observation group was significantly lower than that in the control group[2.5％(1/40)vs 20.0％(8/40)](P＜0.05).There were no statistically significant differences in the incidences of other adverse reactions between the two groups(both P＞0.05).The satisfaction of doctors in the observation group was significantly higher than that in the control group[97.5％(39/40)vs 52.5％(21/40)](P＜0.001).There was no statistically significant difference in patient satisfaction between the two groups(P=0.709).Conclusion The new double-tube laryngeal mask airway can ensure oxygenation and has good safety in the treatment of esophageal and gastric varices sclerotherapy combined with tissue adhesive injection in patients with liver cirrhosis.