Analysis of the influencing factors on the occurrence of heart failure after dual chamber pacemaker implantation
Gerile
Guo Xinjun
Zhao Ping
Teng Fei
Liu Hongya
Xu Lidong
Abstract：Objective To analyze the influencing factors on the occurrence of heart failure after dual chamber pacemaker implantation.Methods A total of 100 patients who were installed permanent atrial and ventricular dual sensing dual pacing dual response(DDD)pacemaker for the first time in the Department of Cardiovascular Medicine,Inner Mongolia Autonomous Region People's Hospital from April 2020 to October 2021 were selected as the research objects,and the proportion of ventricular pacing was more than 40％.Echocardiography,electrocardiogram,dynamic electrocardiogram,N-terminal pro-brain natriuretic peptide(NT-proBNP)and 6 min walking test(6MWT)distance were measured before operation and 3 and 6 months after operation.After the follow-up,cardiac function parameters of patients were detected.Multivariate Logistic regression model was established to analyze the influencing factors of postoperative heart failure.Results The QRS duration,left ventricular end systolic diameter(LVESD),left ventricular end diastolic diameter(LVEDD)and NT-proBNP were significantly higher,left ventricular ejection fraction(LVEF)was significantly lower,and 6MWT distance was significantly shorter at 6 months after operation than those before operation(all P＜0.05).After 6 months of follow-up,a total of 41 patients with heart failure were found in 100 patients.The QRS duration,left atrial diameter,LVESD,LVEDD,left ventricular end systolic volume(LVESV),left ventricular end diastolic volume(LVEDV)and NT-proBNP in the heart failure group were higher than those in the non-heart failure group[(156±10)ms vs(113±11)ms,(39.1±2.1)mm vs(37.2±1.8)mm,(34±4)mm vs(33±4)mm,(50±9)mm vs(47± 4)mm,(46±6)ml vs(42±4)ml,(109±7)ml vs(106±7)ml,(811±208)ng/L vs(588±210)ng/L],the LVEF in the heart failure group was lower than that in the non-heart failure group[(48±4)％vs(59±4)％],and the 6MWT distance in the heart failure group was shorter than that in the non-heart failure group[(366±54)m vs(538±58)m](all P＜0.05).Multivariate Logistic regression analysis showed that age,QRS duration,LVESV,LVEDV,LVEF,NT-proBNP and 6MWT distance were independent risk factors for postoperative heart failure in patients(all P＜0.05).Conclusion Age,NT-proBNP,6MWT distance and other cardiac function parameters were closely related to the occurrence of heart failure after DDD pacemaker implantation.
Keywords：Dual chamber pacemakerHeart failureInfluencing factors
Publication Date：2024-04-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 490-494 )