Effect of novel coronavirus infection on major adverse cardiovascular events during hospitalization in patients with acute coronary syndrome
Yan Hangyu
Fan Chu
Li Dan
Dong Shutong
Liu Jielin
Li Zhizhong
Huang Ji
Abstract：Objective To investigate the effect of novel coronavirus infection on major adverse cardiovascular events(MACE)during hospitalization in patients with acute coronary syndrome(ACS).Methods Clinical data of 147 patients with ACS admitted to Beijing Anzhen Hospital,Capital Medical University from December 2022 to January 2023 were analyzed.Patients were divided into the novel coronavirus infection group(98 cases)and the non infection group(49 cases)according to whether it was infected with novel coronavirus.The clinical characteristics and incidence of MACE during hospitalization were compared between the two groups.Cox regression model was used to analyze the independent correlation between novel coronavirus infection and MACE during hospitalization.Results The age,proportion of females,D-Dimer level and length of stay of novel coronavirus infection group were greater/higher/longer than those of non infection group and the lymphocyte level and the proportion of revascularization after admission were lower than those of non infection group(all P＜0.05).The incidence of MACE during hospitalization of novel coronavirus infection group was significantly higher than that of non infection group[32.7％(16/49)vs 11.2％(11/98)](P=0.002).Multivariate Cox regression analysis showed that novel coronavirus infection was independently associated with MACE during hospitalization in patients with ACS(hazard ratio=3.217,95％ confidence interval:1.151-8.987,P=0.031).Conclusion Novel coronavirus infection can increase the incidence of MACE during hospitalization in patients with ACS.
Keywords：Acute coronary syndromeNovel coronavirus infectionClinical characteristicsDuring hospitalization
Publication Date：2024-03-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 331-335 )