Comparative study on the stability of pacing parameters between left bundle branch pacing and right ventricular septum pacing in patients with bradyarrhythmia
Li Haiwei
Yuan Zhongyu
Wang Zefeng
Sun Weiping
Cui Naiyuan
Liu Yutong
Zhang Xiaoping
Wu Yongquan
Abstract：Objective To compare the stability of pacing parameters between left bundle branch pacing(LBBP)and right ventricular septal pacing(RVSP)in patients with bradyarrhythmia.Methods The clinical data of patients with bradyarrhythmia who underwent implantation of permanent dual-chamber pacemaker in Beijing Anzhen Hospital,Capital Medical University from January 2019 to August 2022 were retrospectively collected.According to the ventricular lead implantation site,patients were divided into RVSP group(155 cases)and LBBP group(106 cases).The baseline clinical data and programmed parameters(ventricular sensing,ventricular threshold,ventricular impedance)were collected and compared between the two groups after operation and at 1-year follow-up.Results Left ventricular end diastolic diameter and left ventricular endsystolic diameter were larger in the LBBP group than those in the RVSP group(both P=0.002).There was no significant difference in the proportion of sick sinus syndrome and atrioventricular block between the two groups(both P＞0.05).After operation,the QRS width in LBBP group was significantly narrower than that in RVSP group[(110±21)ms vs(140±29)ms](t=8.204,P＜0.001).After operation,there was no significant difference in ventricular sensing between the two groups(P=0.514).The ventricular threshold in LBBP group was higher than that in RVSP group[(0.86±0.33)V vs(0.69±0.22)V],and the ventricular impedance was lower than that in RVSP group[(734±200)Ω vs(913±276)Ω].The differences were statistically significant(all P＜0.001).The 1-year follow-up results of the two groups showed that the ventricular sensing and ventricular threshold in the LBBP group were higher than those in the RVSP group,and the ventricular impedance was lower than that in the RVSP group(all P＜0.05).The proportion of ventricular pacing in LBBP group was higher than that in RVSP group,but there was no significant difference between the two groups(P=0.064).Conclusion In patients with bradyarrhythmia with permanent pacemaker implantation,RVSP and LBBP pacing parameters are safe and stable.Compared with RVSP,LBBP is beneficial to maintain good cardiac systolic synchrony.
Keywords：BradyarrhythmiasRight ventricular septal pacingLeft bundle branch pacingPacing parameters
Publication Date：2023-12-08
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1783-1787 )