Evaluation of carotid plaque stability by contrast-enhanced ultrasound in patient with diabetic retinopathy
Zhang Xuemei
Zhao Ying
Zhao Xin
Lou Ping
Wang Junxiang
Zhang Yang
Shi Rui
Abstract：Objective To explore the value of contrast-enhanced ultrasound in the evaluation of carotid plaque stability in patients with type 2 diabetes and diabetic retinopathy.Methods From September 2018 to March 2019,69 patients with type 2 diabetes and diabetic retinopathy,including 40 cases of non-proliferative diabetic retinopathy(NPDR group) and 29 cases of proliferative diabetic retinopathy(PDR group),and 32 type 2 diabetic patients without retinopathy(NDR group) were found carotid plaque by ultrasound examination in Shaanxi Provincial People's Hospital.Contrast-enhanced ultrasound was performed in all patients.Carotid intima-media thickness(IMT),culprit plaque thickness and contrast-enhanced ultrasound score of culprit plaque were analyzed.Results Most patients showed hypoechoic plaques.Carotid IMT was greater with PDR than with NDR and NPDR [(1.10 ± 0.15)mm vs (0.96 ±0.14),(0.99 ± 0.12) mm] (both P ＜ 0.05).There was no significant difference in the thickness of culprit plaque among the 3 groups(P ＞ 0.05).The ultrasound contrast score of culprit plaque was mostly 1 in NDR,NPDR and 3 in PDR.Conclusions Carotid plaques are mainly hypoechoic in diabetic patients with or without retinopathy.IMT increases in PDR patients,causing angiogenesis that may increase the vulnerability of plaques.
Keywords：Type 2 diabetes mellitusContrast-enhanced ultrasoundRetinopathy
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1817-1820 )