Effect of stellate ganglion block on postoperative rehabilitation of carotid artery adventitia removal in children with unilateral spastic cerebral palsy
Yuan Yingchuan
Luan Xinping
Yan Baofeng
Abstract：Objective To investigate the effect of stellate ganglion block on the rehabilitation of children with unilateral spastic cerebral palsy after carotid artery adventitia removal.Methods Sixty-five children with unilateral spastic cerebral palsy who underwent carotid artery adventitia removal in the Second Affiliated Hospital of Xinjiang Medical University from September 1st,2016 to September 1st,2018 were randomly divided into control group(31 cases) and block group(34 cases).The control group had routine rehabilitation and function training after surgery.The block group was treated with stellate ganglion block once a week on the basis of routine therapy.Local cerebral blood flow perfusion weighted imaging (PWI) and magnetic resonance spectrum (MRS) examination were performed before,1 week and 6 months after surgery.Recovery of athletic ability was evaluated by Fine Motor Function Measure(FMFM) and Gross Motor Function Measure(GMFM-66).Results Six months after surgery,blood flow measured by PWI of frontal lobe,central anterior gyrus,basal ganglia and thalamus in block group were significantly higher than those in control group[(68.6 ±4.3)ml/(min · 100 g) vs (64.7 ±5.2)ml/(min · 100 g),(54.9 ±3.4)ml/(min · 100 g) vs (46.2 ±2.4)ml/(min · 100 g),(22.3 ±5.0)ml/(min · 100 g) vs (19.7 ± 5.4)ml/(min · 100 g),(36.1 ±4.3)rnl/(min · 100 g) vs (33.4 ±3.7)ml/(min · 100 g)] (all P ＜0.05).Peak-to-peak ratios of N-acetylaspartic acid to choline compounds and N-acetylaspartic acid to creatine measured by MRS of basal ganglia and thalamus in block group were significantly higher than those in control group [(0.70 ±0.09) vs (0.60 ±0.09),(1.13 ±0.17) vs (1.03 ±0.10)] (both P ＜0.05).Scores of FMFM and GMFM-66 in block group were significantly higher than those in control group[(80 ± 12) vs (74 ± 11),(88 ±7) vs (83 ±6)](both P ＜ 0.05).Conclusion Stellate ganglion block can improve blood supply to partial brain regions,relieve limb spasm and improve motor function in children with unilateral spastic cerebral palsy treated by carotid artery adventitia removal.
Keywords：Unilateral spastic cerebral palsyCarotid adventitia resectionStellate ganglion block
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1808-1812 )