Analysis on contributory factors of carotid artery atherosclerosis in middle-aged and old people undergoing physical examination
Yu Wen
Hu Rong
Xue Yuan
Sun Jiayi
Abstract：Objective To investigate the influencing factors of carotid artery atherosclerosis ( CAS ) in middle-aged and old people undergoing physical examination. Methods A cross-sectional study was performed on 948 middle-aged and old residents(45-75 years old) who had physical examination in Beijing Anzhen Hospital, Capital Medical University from January 2014 to December 2017. All subjects had carotid ultrasound and blood biochemical test. Previous medical history and lifestyle characteristics were analyzed. Results The detection rate of CAS was 69. 8％(662/948). Age, rates of male, hypertension, smoking, excessive alcohol consumption, lack of physical activity, dietary imbalance and serum homocysteine level in CAS group were significantly higher than those in normal group[(60 ± 7)years vs (53 ± 6)years, 61. 3％(406/662) vs 48. 6％(139/286), 80. 1％(530/662) vs 39. 5％ ( 113/286 ) , 33. 8％ ( 224/662 ) vs 12. 9％ ( 37/286 ) , 32. 3％ ( 214/662 ) vs 14. 3％ ( 41/286 ) , 56. 9％(377/662) vs 35. 3％(101/286), 61. 2％(405/662) vs 25. 9％(74/286), (19 ± 6)μmol/L vs (14 ± 4)μmol/L](all P < 0.05). The detection rate of CAS in 60-75 years old people was higher than that in 45-59 years old people[78. 0％(333/427) vs 63. 1％(329/521)](P<0. 001). The detection rate of CAS in males was higher than that in females[74. 5％(406/545) vs 63. 5％(256/403)](P<0. 001). Logistic regression analysis showed that age(odds ratio =1. 076, 95％ confidence interval: 1. 064-1. 102, P <0. 001), gender (odds ratio=1. 714, 95％ confidence interval: 1. 081-2. 695, P =0. 024), hypertension(odds ratio =1. 453, 95％ confidence interval: 1. 024-2. 315, P <0. 001), smoking(odds ratio =2. 135, 95％ confidence interval:1. 281-4. 143, P=0. 018), excessive alcohol consumption(odds ratio=1. 564, 95％ confidence interval:1. 157-3. 168, P=0. 021), lack of physical activity(odds ratio=1. 466, 95％ confidence interval:1. 047-2. 154, P=0. 032), dietary imbalance(odds ratio=2. 015, 95％ confidence interval:1. 562-3. 473, P<0. 001) and serum homocysteine level(odds ratio =0. 423, 95％ confidence interval: 0. 237-0. 651, P =0. 004) were influencing factors of CAS in middle-aged and old people. Conclusions Incidence of CAS is associated with age and male gender in middle-aged and old people. In addition, many controllable factors such as unhealthy lifestyle and habits may affect the occurrence and development of CAS. Strengthening health management is of great significance to the prevention and control of CAS.
Keywords：Carotid atherosclerosisInfluencing factors
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1492-1496 )