Risk factors of venous thromboembolism after lung cancer surgery in elderly patients
Li Hui
Luo Yinglin
Wu Shengbin
Zhou Mingming
Abstract：Objective To investigate the risk factors of venous thromboembolism( VTE) after lung cancer surgery in elderly patients. Methods A total of 240 elderly patients with lung cancer were enrolled from January 2016 to September 2018 in People′s Hospital of Baise, Guangxi Zhuang Autonomous Region. Clinical data including gender, body mass index, smoking history, coronary heart disease, hypertension, diabetes, white blood cell count( WBC) ,platelet count( PLT) , D-dimer, radiotherapy, chemotherapy, hospitalization time and history of venous embolism were collected. Incidence of VTE after lung cancer resection was recorded. Risk factors of VTE were analyzed by single factor method and multivariate logistic regression. Results Incidence of VTE was 11. 2％(27/240). There were no significant differences of gender, body mass index, coronary heart disease, WBC abnormality, PLT abnormality, radiotherapy and hospitalization time between VTE group and non-VTE group (all P>0. 05). There were significant differences of smoking history, hypertension, diabetes, D-dimer abnormality, chemotherapy and venous embolism history between groups(all P<0. 05). Logistic regression analysis showed that smoking history, D-dimer abnormality, chemotherapy and venous embolism history were risk factors of VTE( odds ratio=1. 986, 2. 264, 1. 537, 1. 729; 95％ confidence interval: 1. 465-2. 896, 1. 638-3. 274, 1. 187-1. 902, 1. 286-2. 371;P=0. 012, 0. 003, 0. 041, 0. 027). Conclusion Occurrence of VTE in elderly patients after lung cancer resection can be influenced by many factors; smoking history, D-dimer abnormality, chemotherapy and venous embolism history are risk factors of VTE.
Keywords：Lung cancerVenous thromboembolismRisk factors
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1484-1487 )