Risk factors and etiological classification of cerebral infarction in young adults
Wang Li
He Xiaofen
Wang Lifeng
Liu Guangzhi
Zhang Zhuo
Abstract：Objective To analyze the risk factors and etiological classification in young patients with cerebral infarction.Methods From January 2010 to December 2018,5 120 patients with acute cerebral infarction were admitted to neurology ward of Beijing Anzhen Hospital,Capital Medical University.Among them,337 young patients and 337 matched (1:1) middle-aged and old patients were selected.Age,sex,smoking,alcohol consumption,comorbidities of diabetes,dyslipidemia,hypertension,heart disease,stroke,hyper-homocysteine (Hcy) and sleep apnea syndrome were recorded.Risk factors and etiological types of cerebral infarction were analyzed.Results Prevalence rates of cerebral infarction risk factors in young patients from high to low were male,hypertension,smoking history,hyperlipidemia,history of alcohol consumption,hyper-Hcy,diabetes,heart disease history,stroke/family history,hyperuricemia,sleep apnea syndrome and migraine.Prevalence rates of cerebral infarction risk factors in middle-aged and old patients from high to low were hyperlipidemia,hypertension,male,smoking history,diabetes,heart disease history,stroke/family history,history of alcohol consumption,hyper-Hcy,hyperuricemia,sleep apnea syndrome and migraine.Proportions of male,smoking history,history of alcohol consumption and hyper-Hcy in young patients were higher while the proportions of hypertension,diabetes,hyperlipidemia,heart disease history,stroke/family history were lower than those in middle-aged and old patients [81.9％ (276/337) vs 70.3％ (237/337),64.4％ (217/337) vs 49.3％ (166/337),38.3％ (129/337) vs 23.7％ (80/337),37.4％ (126/337) vs 18.4％ (62/337);66.2％ (223/337) vs 78.9％ (266/337),25.2％(85/337) vs 40.4％ (136/337),49.3％ (166/337) vs 81.0％ (273/337),16.3％ (55/337) vs 37.7％ (127/337),12.5％ (42/337) vs 32.6％ (110/337)] (all P ＜ 0.05).Atherosclerosis type of cerebral infarction took the highest ratio among young patients;small artery occlusion type accounted for 32.0％ (108/337);unexplained type accounted for 12.8％ (43/337);cardiogenic type accounted for 10.1％ (34/337).Males took a large ratio in young patients with unexplained type of cerebral infarction.Among middle-aged and old patients,atherosclerosis type and small artery occlusion type of cerebral infarction accounted for high ratios.Conclusions Young men are more likely to suffer from cerebral infarction than women.Cerebral infarction in young adults are associated with various risk factors.Atherosclerosis type of cerebral infarction is the most common etiological type.It is of great significance for the prevention and treatment of young stroke to strengthen health education on smoking and alcohol cessation,promote healthy diet and raise the awareness of stroke risk factors among young people.
Keywords：Cerebral infarctionRisk factorsEtiology typing
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1173-1176 )