An open-label, multi-center, random-control clinical study of Xiangju capsules in treatment of influenza
Du Xiaobing
Chen Qianhua
Xiao Yao
Zhang Xueqin
Xia Jinghong
Liu Shuang
Abstract：Objective To evaluate the efficacy and safety of Xiangju capsules in the treatment of influenza.Methods From January 2017 to November 2018,148 patients with acute simple influenza were enrolled in Beijing Anzhen Hospital,Capital Medical University,Peking University International Hospital,Beijing Fengtai Hospital and Aviation General Hospital.The patients were randomly divided into observation group(76 cases) and control group(72 cases).The control group took Lianhua Qingwen capsules,4 capsules,3 times a day;the observation group took Xiangju capsules,2-4 capsules,3 times a day.Both groups were treated for 5 days.Improvement of clinical symptoms,clinical efficacy and adverse drug reactions were analyzed.Results Two patients in control group were dropped out during the study.There was no significant difference of clinical symptom scores between groups before and after treatment(all P ＞0.05).After treatment,clinical symptom scores significantly reduced in both groups compared to those before treatment(both P ＜ 0.01).Intentional analysis showed no significant difference of the recovery rate and total effective rate between control group and observation group [63.9％ (46/72) vs 68.4％ (52/76),83.3％ (60/72) vs 86.8％ (66/76)] (all P ＞ 0.05).There was no serious adverse reaction during treatment in both groups.Conclusion Xiangju capsules is safe and effective in the treatment of influenza.
Keywords：InfluenzaXiangju capsulesLianhua Qingwen capsules
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 981-983 )