Gender differences in hospitalized patients with acute myocardial infarction and risk factors of in-hospital death after percutaneous coronary intervention

Qiao Manli; Bi Qi

doi:10.3760/j.issn.1673-4777.2019.06.004

Abstract：Objective To analyze the clinical features between patients with different genders with acute myocardial infarction (AMI) and the risk factors of in-hospital death after percutaneous coronary intervention (PCI).Methods A total of 2 447 AMI patients who underwent PCI in Beijing Anzhen Hospital,Capital Medical University from January 1 st to December 31st,2017 were retrospectively analyzed.Clinical data were analyzed between males and females.Risk factors of in-hospital death were analyzed by logistic regression.Results There were 2 017 males and 430 females.Age,hospitalization time,onset to visit time,rates of hypertension,diabetes,hyperlipidemia,Killip grade≥ 3,multi-vessel disease and the number of stent implantation in female patients were significantly higher than those in male patients;rates of medical insurance payment and smoking history in female patients were significantly lower than those in male patients(all P ＜ 0.05).There were 16 in-hospital deaths and 2 431 survivals.Multivariate logistic regression showed that age ≥ 65 years [odds ratio (OR) =3.25,95％ confidence interval(C1):1.63-8.81,P =0.006],Killip grade ≥ 3 (OR =3.52,95％ CI:1.36-5.28,P =0.002) and multi-vessel disease (OR =2.04,95％ CI:1.33-4.37,P =0.010) were independent risk factors of in-hospital mortality in AMI patients undergoing PCI.Conclusions Female patients with AMI are older and have more delays in pre-hospital treatment,prolonged hospital stay,severer coronary lesion and higher mortality than males.Advanced age,severe heart failure and multi-vessel disease are independent risk factors of in-hospital mortality after PCI.