Therapeutic effect of volume-rotation intensity-modulated radiotherapy on glioma and the effect on quality of life
Gu Guoqiang
Xiong Minrong
Sun Yunfeng
Li Qingbo
Abstract：Objective To explore the therapeutic effect of volume-rotation intensity-modulated radiotherapy on patients with glioma and the effect on quality of life. Methods A total of 65 patients with glioma diagnosed in Huzhou Third People's Hospital,Zhejiang Province,from March 2016 to March 2018 were randomly divided into observation group(33 cases) and control group(32 cases). The control group was treated with intensity-modulated conformal radiotherapy; the observation group was treated with volume-rotation intensity-modulated radiotherapy. Clinical efficacy,quality of life score,median survival and adverse reactions were analyzed. Results After treatment,the total effective rate in observation group was significantly higher than that in control group@@[90. 9％(30 /33) vs 62. 5％ (20 /32 ) ](P < 0.05 ). Scores of physical function,role function,emotional function,social function and cognitive function were significantly improved after treatment in both groups and the scores in observation group were significantly higher than those in control group(all P < 0.05). Median survival time in observation group was significantly longer than that in control group[(18. 4 ± 3. 3) months vs (14. 2 ± 2. 1) months](P < 0. 01). Incidence of adverse reactions in observation group was significantly lower than that in control group[18. 2％ (6 /33) vs 65. 6％ (21 /32) ](P < 0. 01). Conclusion Volume-rotation intensity-modulated radiotherapy is effective in the treatment of glioma and it can significantly improve the quality of life.
Keywords：GliomaVolume-rotation intensity-modulated radiotherapyQuality of life
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 703-705 )