Clinical effect of Xueluokang decoction lavipeditum on diabetic peripheral neuropathy of cold-stagnation and blood-stasis type
Li Bowu
Sun Guangrong
He Zhongchen
Li Jun
Kang Lihua
Tan Fang
Wang Yijiao
Chen Hongdong
Li Xueli
Abstract：Objective To evaluate the clinical effect of Xueluokang decoction lavipeditum on diabetic peripheral neuropathy(DPN) of cold-stagnation and blood-stasis type.Methods From January 2017 to January 2018,70 DPN patients in Beijing Hepingli Hospital were randomly divided into observation group and control group,with 35 cases in each group.Both groups were treated by rational diet,exercise guidance,hypoglycemic drugs and mecobalamin tablets.The control group was given lavipeditum with warm water and the observation group had lavipeditum with Xueluokang decoction once daily for 4 weeks.Total curative effect,score of Toronto Clinical Scoring System(TCSS),vibration perception threshold(VPT) were assessed and adverse reactions were observed.Results Total effective rate in observation group was significantly higher than that in control group[85.7％ (30/35) vs 60.0％ (21/35)] (P ＜ 0.05).After treatment,TCSS score and VPT of bilateral lower limbs were lower than those before treatment and they were lower in observation group than those in control group [(3.2 ± 0.8) vs (6.2 ± 0.6),left VPT:(14.1 ±1.9)V vs (18.2±2.1)V,right VPT:(13.5 ±1.5)V vs (18.0 ± 1.6)V] (all P＜ 0.05).There was no significant difference of the incidence of adverse reactions between groups (P ＞ 0.05).Conclusion Xueluokang decoction lavipeditum can alleviate clinical symptoms,improve TCSS score and VPT in DPN oatients.
Keywords：Diabetic peripheral neuropathyXueluokang decoctionExternal therapy of traditional Chinese medicineVibration perception threshold
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 558-561 )