Clinical features and misdiagnosis of airway involvement in relapsing polychondritis
Yang Xichao
Ba Yanna
Wu Zhenbiao
Lyu Tingting
Abstract：Objective To explore the clinical features and misdiagnosis profile of airway involvement in relapsing polychondritis(RP).Methods Clinical data of 80 patients diagnosed of RP in the First Affiliated Hospital of Air Force Military Medical University from January 2010 to January 2017 were retrospectively analyzed.According to whether they were misdiagnosed on the first admission,the patients were divided into correct diagnosis group(48 cases) and misdiagnosis group(32 cases).Results The first three airway manifestations of RP were dyspnea or wheezing [62 cases (77.5％)],hoarseness [48 cases (60.0％)],cough and sputum [45 cases (56.2％)].Rate of auricular cartilage inflammation in the misdiagnosis group was significantly lower than that in the correct diagnosis group[22.5％ (9/32) vs 52.5％ (21/48)] (P =0.012).Rate of laryngeal,tracheal and main bronchial simultaneous involvements in the correct diagnosis group was higher than that in the misdiagnosis group[41.7％ (20/48) vs 15.6％ (5/32)] (P =0.002).Airway involvement of RP can be misdiagnosed of asthma(10 cases),pharyngitis and bronchitis(11 cases).Tracheotomy rate in the misdiagnosis group was high [81.2％ (26/32)].Conclusion Extensive airway involvement and auricular cartilage inflammation show some indicative value in the early diagnosis of RP.
Keywords：Recurrent polychondritisAirway involvementMisdiagnosisClinical manifestation
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 537-540 )