Clinicopathological characteristics of papillary thyroid carcinoma and risk factors of central lymph node metastasis
Zhao Tiezheng
Ren Yi
Wang Yuwen
Abstract：Objective To analyze the clinical and pathological characteristics of papillary thyroid carcinoma (PTC) and the risk factors of central lymph node metastasis(CLNM).Methods Clinical data of 130 PTC patients admitted to Huanghua Municipal People's Hospital from January 2010 to June 2018 were retrospectively analyzed.Risk factors of CLNM were analyzed by logistic regression.Results There were 61 cases (46.9％) having CLNM.Single-factor analysis showed that tumor size ＞ 1 cm(P =0.001),Hashimoto thyroiditis (P =0.006),multifocal thyroiditis (P ＜ 0.001) and thyroid capsule invasion (P ＜ 0.00 1) were related with CLNM.Multi-factor logistic analysis showed that tumor size ＞ 1 cm(odds ratio =0.382,95 ％ confidence interval:0.178-0.818,P =0.013),multifocal thyroiditis (odds ratio =0.206,95％ confidence interval:0.093-0.421,P =0.002) and thyroid capsule invasion(odds ratio =0.348,95％ confidence interval:0.162-0.750,P =0.007) were independent risk factors of CLNM.Conclusion PTC patients with tumor size ＞ 1 cm,multifocal tumor and thyroid capsule involvement should have tumorectomy plus central lymph node dissection.
Keywords：Papillary thyroid carcinomaCentral lymph node metastasis
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 389-391 )