Relation between waist-to-hip ratio, waist circumference and prognosis of patients undergoing selective percutaneous coronary intervention
Wang Jianlong
Zhao Yingxin
Liu Yuyang
Zhai Guangyao
Zhou Yujie
Abstract：Objective To analyze the relation between waist-to-hip ratio (WHR),waist circumference (WC) and prognosis in patients with coronary heart disease (CHD) undergoing selective percutaneous coronary intervention(PCI).Methods A total of 650 consecutive CHD patients with coronary artery stenosis more than 75％ undergoing selective PCI in Beijing Anzhen Hospital,Capital Medical University between July and December 2011 were involved.Baseline characteristics and measurements were collected.All patients were classified into tertiles of WC or WHR.Primary end-points included death,non-fatal myocardial infarction,target vessel revascularization and stroke during the 1st year after procedure.Secondary end-point was cardiovascular readmission.Results The cutoff values of tertiles of WHR were 0.91 and 0.97 for men,0.90 and 0.95 for women.The categorization based on WHR in the whole cohort was low WHR group(men:≤0.91;women:≤0.90),middle WHR group(men:0.92-0.97;women:0.91-0.95) and high WHR group(men:＞ 0.97;women:＞ 0.95).The cutoff values of tertiles of WC were 89,96 cm for men and 85,92 cm for women.The categorization based on WC was low WC group(men:≤89 cm;women:≤85 cm),middle WC group(men:90-96 cm;women:86-92 cm)and high WC group(men:＞ 96cm;women:＞ 92 cm).Incidences of target vessel revascularization and primary end-point events in the high and middle WHR groups were higher than those in the low WHR group [8.9％ (19/214),6.3％(14/224) vs 2.4％ (5/212);13.1％ (28/214),8.9％ (20/224) vs 3.8％ (8/212)];incidence of cardiovascular readmission in the high WHR group was higher than that in the middle and low WHR groups [19.6％ (42/241) vs 7.5 ％ (16/212),12.5 ％ (28/224)] (all P ＜ 0.05).Event-free survival rate in the high WHR group was the lowest in survival analysis (P =0.003).Diabetes history was associated with high risk of primary end-point events after PCI(hazard ratio =2.04;95％ confidence interval:1.21-3.45,P ＜ 0.001).WHR rise was positively related with primary end-point events;the hazard ratio increased in the middle WHR group (hazard ratio =2.43;95％ confidence interval:1.07-5.52,P =0.034) and high WHR group (hazard ratio =3.67;95％ confidence interval:1.67-8.05,P ＜ 0.001).Conclusion WHR can be a predictive index for the outcome of CHD patients with selective PCI.
Keywords：Percutaneous coronary interventionObesityWaist-to-hip ratioWaist circumference
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 161-165 )