Long-term outcomes of patients with acute coronary syndrome complicated with cancer undergoing percutaneous coronary intervention
Ma Yue
Liu Fang
Sun Yan
Ma Xiaoteng
Lyu Sai
Cheng Yujing
Du Yu
Yang Lixia
Wang Zhijian
Liang Jing
Zhou Zhiming
Zhou Yujie
Abstract：Objective To investigate the differences between lung cancer and other cancers in acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI) in terms of baseline characteristics,procedural characteristics and long-term outcomes.Methods Totally 233 adult ACS patients with cancer who underwent PCI in Beijing Anzhen Hospital,Capital Medical University from January 2014 to December 2016 were included.They were divided into 2 groups according to the cancer types:ACS with lung cancer group (n =42) and ACS with other cancers group(n =191).Baseline data,previous medical history,cardiovascular risk factors,history of cancer,procedural records of PCI and long-term follow-up data were analyzed.Results Male rate,rates of previous radiotherapy and chemotherapy in ACS with lung cancer group were higher than those in ACS with other cancers group[83.3％ (35/42) vs 60.2％ (115/191),31.0％ (13/42) vs 12.0％ (23/191),40.1％ (17/42) vs 23.0％ (44/191)] (all P ＜ 0.05).There were no significant differences of age,body mass index,previous history of illness,accessory examination and drug treatment between groups(P ＞ 0.05).Incidence of coronary artery calcification in ACS with lung cancer group was higher than that in ACS with other cancers group [26.2％ (11/42) vs 13.1％ (25/191)] (P ＜0.05).There were no significant differences of ACS type,number of diseased vessels,drug-eluting stent implantation rate,number of stents and other types of special coronary artery lesions between groups (P ＞ 0.05).During (2.4 ± 0.9) years of follow-up,32 patients (13.7％) were lost.Cardiovascular mortality in ACS with lung cancer group was higher than that in ACS with other cancers group [8.1％ (3/37) vs 1.2％ (2/164)] (P ＜0.05).There were no significant differences of the incidences of major adverse cardio-cerebrovascular events,all-cause mortality,cancer mortality,cardiogenic shock and cardiovascular readmission between groups(all P ＞ 0.05).Conclusion Lung cancer shows a high prevalence in ACS patients undergoing PCI with poor long-term cardiovascular outcomes.
Keywords：Lung neoplasmsAcute coronary syndromePercutaneous coronary interventionCardiovascular outcome
Publication Date：2019-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 10-14 )