Rationality of drug use in children with bronchial pneumonia after evidence-based intervention
Liu Jianhong
Yu Jiajie
Xie Yong
Li Youping
Zhang Weidong
Xu Ting
Wu Min
Lu Jing
Li Xiao
Abstract：Objective To investigate the rationality of drug use in children with bronchial pneumonia after evidence-based intervention.Methods Medical records of children with the first diagnosis of bronchial pneumonia who discharged between 1st,January and 31st,December in 2016 in Karamay Central Hospital were extracted from the electronic medical record database.Evidence-based medication intervention was performed during 2016 based on the statistical data in 2014.Hospitalization time,expenses and medication information were analyzed.The improvement of medication reasonableness was analyzed between 2014 and 2016.Results After the intervention,per capita hospitalization time in 2016 (n =904) was significantly shorter than that in 2014 (n =890) [(6.1 ±2.1)d vs (7.1 ± 2.6)d] (P ＜ 0.001);per capita drug species in 2016 were less than those in 2014 [(7.1 ± 2.2) vs (8.3 ± 3.5)].In 2016,the combined use rate of antimicrobial agents fell by 12.27％ compared to that in 2014.The use ratio of salbutamol sulfate tablets and aminophylline tablets was 1.34％ (11/820) in 2016,which fell by 83.97％ compared to that in 2014.The use ratio of methylprednisolone sodium succinate for injection was 8.91％ (80/898) in 2016,which fell by 76.74％ compared to that in 2014.Conclusions Evidence-based intervention helps adjust clinical pathway and promote rational drug use in children with bronchial pneumonia.After evidence-based practice,hospitalization days and drug species decrease;irrational drug uses such as antibacterial combination and glucocorticoid for injection are improved.
Keywords：BronchopneumoniaRational drug useEvidence-based intervention
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1646-1650 )