Effect and safety of Tanreqing injection combined with antibiotics in treatment of hospital acquired pneumonia: a meta analysis
Fan Liping
Kong Xiangwen
Lu Shu
Qiang Sisi
Abstract：Objective To assess the clinical effect and safety of Tanreqing injection combined with antibiotics in the treatment of hospital acquired pneumonia (HAP).Methods Randomized controlled trials of Tanreqing injection combined with antibiotics treating HAP were retrieved from Cochrane,PubMed,Embase,China National Knowledge Infrastructure,Wanfang Data and Chinese Sci-tech Periodical Full-text Database.Quality of the literatures was evaluated by the Jadad score.Statistical analysis was performed using the RevMan 5.3 software.Results Eight trials involving 566 patients were included.Results of meta analysis showed that the total effectiveness(odds ratio =3.40,95％ confidence interval:2.09-5.53,P ＜ 0.05) and defervescence time(standardized mean difference =-1.26,95％ confidence interval:-1.48 to-1.05,P ＜ 0.05) in Tanreqing injection + antibiotics group were superior to those in antibiotics-alone group.Funnel plot showed small bias in both total efficiency and defervescence time analysis.Conclusions Tanreqing combined with antibiotic treating HAP can improve the total efficiency and shorten defervescence time.
Keywords：Hospital acquired pneumoniaTanreqing injectionAntibioticsMeta analysis
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1642-1645 )