Clinical features of Takayasu's arteritis with peripheral artery involvement
Li Taotao
Du Juan
Gao Na
Liao Hua
Guo Yanqiu
Pan Lili
Abstract：Objective To investigate the clinical features of Takayasu's arteritis with peripheral artery involvement.Methods Clinical records of 32 patients with Takayasu's arteritis and peripheral artery lesions in Beijing Anzhen Hospital,Capital Medical University from January 2012 to June 2017 were reviewed.General information,main symptoms and signs,imaging and laboratory results were analyzed.Results There were 6 males and 26 females;the male to female ratio was about 1 ∶ 4.There was no significant difference of age between males and females[(35 ± 12)years vs(39 ± 14)years] (P =0.599).Twenty-one(65.6％) patients were treated with glucocorticoids;18 (56.3％) patients were treated with immunosuppressants;8 (25.0％) patients were treated with biological agents;17 (53.1％) patients were treated with antiplatelet agents.Common clinical manifestations were dizziness (n =18,56.2％),limb weakness (n =14,43.8％),pulselessness (n =13,40.6％) and asymmetric blood pressure of limbs (n =11,34.4％).According to angiographic manifestations,type Ⅴ (n =19,59.4％) and type Ⅰ (n =6,18.8％) were the most common types.Peripheral lesions mainly located at axillary artery(n =20,62.5％) and femoral artery(n =13,40.6％).The lesions were characterized by angiostenosis(n =22,68.8％),occlusion (n =10,31.3％),intima-media thickness increase (n =5,15.6％)and aneurysm (n =1,3.1％).There were no significant differences of clinical manifestations,angiographic classifications,lesion locations and characteristics between males and females (P ＞ 0.05).Among laboratory indicators,13 female patients (40.6％) showed erythrocyte sedimentation rate increase;12 patients (37.5％)showed C-reactive protein level increase,including 11 females (42.3％) and 1 male.Conclusions Peripheral artery lesions can be involved in Takayasu's arteritis.Common clinical manifestations of Takayasu's arteritis with peripheral artery involvement are dizziness,limb weakness,pulselessness and asymmetric blood pressure in limbs.There are no significant differences of clinical manifestations,angiographic classifications,lesion locations and characteristics between male and female patients.
Keywords：Takayasu's arteritisPeripheral arteryClinical features
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1299-1302 )