Clinical effect of different operation occasions of laparoscopic cholecystectomy on biliary acute pancreatitis
Pan Deng
Abstract：Objective To investigate the clinical effect of different operation occasions of laparoscopic cholecystectomy on biliary acute pancreatitis.Methods Totally 147 cases of biliary acute pancreatitis (AP) admitted at Yuncheng Central Hospital from January 1 st 2015 to December 31 st 2016 were enrolled.According to the severity of disease,they were divided into mild acute pancreatitis (MAP),mild to severe acute pancreatitis (MSAP) and severe acute pancreatitis(SAP).According to the onset to operation time,the patients were divided into group A1 (＜72 h,n =48),group A2(72 h-＜ 1 week,n =37),group B1 (72 h-2 weeks,n =34) and group B2 (＞ 2 weeks,n =28);patients with MAP and MSAP belonged to group A1 and A2 (n =85);patients with SAP belonged to group B1 and B2 (n =62).Intraoperative blood loss volume,operation time,hospital stay time,medical expense,levels of alanine aminotransferase(ALT),aspartate aminotransferase (AST) and total bilirubin (TBIL) before and 3,7 d after operation,incidences of postoperative complications (pulmonary infection and incision infection) and recurrence of pancreatitis were analyzed.Results Intraoperative blood loss volume,operation time,hospital stay time and medical expense in group B1 and B2 were significantly more/longer/higher than those in group A1 and A2 [(46 ± 4),(47 ± 6) ml vs (32 ± 4),(33 ± 4) ml;(51 ± 4),(53 ± 4) min vs (34 ± 4),(35 ±2)min;(42 ±5),(36 ±5)d vs (10±3),(21 ±5)d;(8.5 ±1.4),(6.9± 1.3)ten thousand yuan vs (2.6 ± 0.4),(3.9 ± 0.5) ten thousand yuan] (P ＜ 0.05).Hospital stay time and medical expense in group A2 were significantly longer/higher than those in group A1;hospital stay time and medical expense in group B2 were significantly shorter/lower than those in group B1 (P ＜ 0.05).Levels of ALT,AST and TBIL 3,7 d after operation were significantly lower than those before operation (P ＜ 0.05);there were no significant differences of ALT,AST and TBIL level among groups (P ＞ 0.05).There were no significant differences of postoperative pulmonary infection rate and incision infection rate among groups(P ＞0.05).Recurrence rate of pancreatitis in group B2 was significantly lower than that in group B1 (P ＜ 0.05).Conclusion Mild biliary AP patients should be operated within 72 h after onset;severe biliary AP patients should be operated 2 weeks after onset.
Keywords：Biliary acute pancreatitisLaparoscopic operationTiming of operation
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1034-1037 )