Clinical characteristics of acute non-ST-segment elevation myocardial infarction in patients with peripheral artery disease history and risk factors of in-hospital adverse events
Kang Yunpeng
Guo Wen
Liu Wenxian
Chen Liying
Kang Tieduo
Abstract：Objective To investigate the clinical characteristics of acute non-ST-segment elevation myocardial infarction(NSTEMI) with peripheral artery disease (PAD) history and the risk factors of in-hospital adverse events.Methods Clinical records of 430 acute NSTEMI patients admitted in Cardiac Care Unit,Beijing Anzhen Hospital,Capital Medical University from January 2010 to November 2017 were reviewed;68 patients had PAD history.Clinical general information,characteristics of coronary artery disease and occurrence of in-hospital adverse events were analyzed.Risk factors of in-hospital adverse events were analyzed by multivariate Logistic regression.Rcsults Ratio of hypertension history,levels of systolic pressure,serum creatinine,total cholesterol,low-density lipoprotein cholesterol and left ventricular end-diastolic dimension (LVEDD) in NSTEMI with PADgroup were significantly higher than those in NSTEMI without PAD group(P ＜ 0.05).Ratio of multivessel diseasein NSTEMI with PAD group was significantly higher than that in NSTEMI without PAD group[15.1％ (10/68) vs 9.7％ (35/362)] (P =0.02).In-hospital death rate in NSTEMI with PAD group was significantly higher than that in NSTEMI without PAD group [7.4％ (5/68) vs 1.9％ (7/362)] (P =0.02).Multivariate logistic regression showed that PAD history(odds ratio =2.396,P =0.024),hypertension history(odds ratio =1.647,P =0.011),LVEDD increase (odds ratio =1.113,P =0.001) and systolic pressure ＜ 90 mmHg (odds ratio =2.223,P =0.025) were independent risk factors of in-hospital adverse events in acute NSTEMI patients.Conclusion Acute NSTEMI patients with PAD history have a high in-hospital death rate;multivessel disease is common;PAD history,hypertension history,LVEDD increase and systolic pressure ＜ 90 mmHg are independent risk factors of in-hospital adverse events.
Keywords：Myocardial infarctionPeripheral arterial diseaseIn-hospital adverse events
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 969-972 )