Risk factors of atherosclerosis in patients with type 2 diabetes
Shi Wei
Chen Lei
Bu Ruifang
Abstract：Objective To analyze the risk factors of atherosclerosis in patients with type 2 diabetes.Methods Clinical data of 200 patients with type 2 diabetes in Wuxi People's Hospital Affiliated to Nanjing Medical University from August 2014 to August 2015 were reviewed;the patients were divided into arteriosclerosis group(n =126) and non-arteriosclerosis group (n =74).General information and biochemical indexes were analyzed.Results Age,course of diabetes,levels of triacylglycerol(TG) and low-density lipoprotein cholesterol (LDL-C) in atherosclerosis group were significantly higher than those in non-arteriosclerosis group[(56 ± 9)years vs (53 ±8)years,(6 ±5)years vs (5 ±4)years,(3.1 ± 1.1) mmol/L vs (2.7 ±0.8) mmol/L,(2.7 ±0.8) mmol/L vs (2.2 ± 0.7) mmol/L];high-density lipoprotein cholesterol (HDL-C) level in atherosclerosis group was significantly lower than that in non-arteriosclerosis group [(0.94 ± 0.19) mmol/L vs (1.01 ± 0.30) mmol/L] (all P ＜ 0.05).Logistic regression analysis showed that advanced age,long course of diabetes,high levels of TG and LDL-C were independent risk factors of arteriosclerosis;high level of HDL-C was a protective factor of arteriosclerosis (P ＜ 0.05).Conclusion Age,course of disease,levels of TG,HDL-C and LDL-C are closely related to the occurrence of arteriosclerosis in patients with type 2 diabetes.
Keywords：Type 2 diabetes mellitusAtherosclerosisRisk factors
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 879-881 )