Clinical effect of budesonide and fomoterol inhalation combined with Suhuang cough capsule on cough variant asthma
Ma Yuanyuan
Aihetiremu Talifu
Cui Yanjie
Abstract：Objective To explore the curative effect of budesonide and fomoterol inhalation combined with Suhuang cough capsule on cough variant asthma (CVA).Methods A total of 80 patients diagnosed of CVA in Urumqi Friendship Hospital from May 2015 to May 2017 were randomly divided into observation group and control group,with 40 cases in each group.The control group was treated with budesonide and fomoterol(160 μg ∶ 4.5 μg)inhalation,2 times/d;the observation group took Suhuang cough capsule (0.45 g) 3 pills/time,3 times/d combined with budesonide and fomoterol inhalation;both groups were treated for 8 weeks.Cough symptom score,pulmonary function indexes [forced vital capacity (FVC),forced expiratory volume in 1 second (FEV1),peak expiratory flow(PEF)] and inflammatory factors [interleukin-6 (IL-6),IL-8,tumor necrosis factor-α (TNF-α)]were analyzed.Results After treatment,cough symptom score in observation group was significantly lower than that in control group[(1.34 ±0.25) vs(2.87 ±0.65)];FVC,FEV1 and PEF in observation group were significantly higher than those in control group [(4.7 ± 0.6) L vs (3.0 ± 0.7) L,(4.5 ± 0.4) L vs (2.7 ± 0.7) L,(8.7 ± 1.0)L/min vs (6.4 ±0.8) L/min];IL-6,IL-8 and TNF-α in observation group were significantly lower than those in control group[(6.4±1.5)ng/L vs (7.7±1.4)ng/L,(7.0±1.5)ng/L vs (9.9±1.4)ng/L,(5.5 ± 1.4) ng/L vs (8.3 ± 1.5) ng/L] (all P ＜ 0.05).Conclusion Budesonide and fomoterol inhalation combined with Suhuang cough capsule treating cough variant asthma can effectively relieve cough symptom,improve lung function and reduce inflammatory factors.
Keywords：Cough variant asthmaBudesonide formoterol inhalationSuhuang cough capsule
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 842-845 )