Clinical efficacy of coronary artery bypass grafting in coronary atherosclerotic heart disease patients with end-stage renal disease
Li Yang
Dong Ran
Rui Hongliang
Liu Taoshuai
Zheng Jubing
Hua Kun
Zhao Yang
Zhang Kui
Huang Qi
Abstract：Objective To analyze the early and long-term outcomes of coronary artery bypass grafting (CABG) in coronary atherosclerotic heart disease (CHD) patients with end-stage renal disease (ESRD).Methods Clinical data of 30 ESRD patients who had CABG from January 2010 to December 2017 in Beijing Anzhen Hospital,Capital Medical University were analyzed;the mean creatinine level was (665 ± 262)μmol/L;the mean glomerular filtration rate was (8 ±4)ml/(min · 1.73 m2);the mean number of coronary artery lesions was (3.1 ±0.8).Twenty-eight patients had off-pump CABG;1 patient had on-pump CABG plus mitral valvuloplasty;1 patient had on-pump CABG plus mitral valve replacement.Surgical and perioperative records,discharge medication and follow-up data were analyzed.Results All patients had continuous renal replacement therapy after surgery.The mean number of bypass grafts was (3.1 ±0.7).Intra-aortic balloon pump was used in 10 patients(33.3％).The perioperative mortality rate was 10.0％ (3/30) including heart failure (2 cases) and ventricular fibrillation (1 case).Two patients(6.7％) had reoperation for hemorrhage.Perioperative atrial fibrillation and myocardial infarction rates were 26.7％ (8/30) and 36.7％ (11/30),respectively.Twenty-three patients (85.2％) took antiplatelet drugs after discharge.Twenty-five patients (92.6％) were followed up for 4 (1,7) years;the all-cause mortality rate was 12.0％ (3/25) including sudden cardiac death(1 case) and pulmonary disease(2 cases);the cardiovascular adverse event rate was 20.0％ (5/25).Conclusion CABG procedure has a high risk in CHD patients with ESRD;the mid-and long-term outcomes are good.
Keywords：Coronary heart diseaseCoronary artery bypass graftingEnd-stage renal failure
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 833-836 )