Surgical treatment of aortic root aneurysm complicated with mitral valve disease in children with Marfan's syndrome
Li Chengnan
Ge Yipeng
Xia Yu
Yang Yi
Guo Shichao
Xiao Fucheng
Liu Yongmin
Zhu Junming
Sun Lizhong
Abstract：Objective To investigate the short-to-midterm outcomes of surgical treatment of aortic root aneurysm complicated with mitral valve disease in children with Marfan's syndrome.Methods Five aortic root aneurysm complicated with mitral valve insufficiency children with Marfan's syndrome had aortic root replacement (Bentall) + mitral valve replacement(MVR) from March 200 to July 2016 in Beijing Anzhen Hospital,Capital Medical University.The average age was (12.0 ± 1.6) years old (10-14 years old).There were 2 males and 3 females.Preoperative left ventricular ejection fraction was (60 ± 4) ％;preoperative left ventricular end-diastolic diameter was (56 ± 9)mm.Postoperative outcomes were followed via phone calls,mails and outpatient visits.Results There was no in-hospital death.Cardiopulmonary bypass time was (154 ± 23)min;aortic clamp time was (114 ± 15)min.Two cases used 21 nun diameter composite mechanical-valved aortic conduit;2 cases used 23 mm diameter composite mechanical-valved aortic conduit;1 case used 25 mm diameter composite mechanical-valved aortic conduit.One case used 25 mm diameter mechanical mitral valve;3 cases used 27 mm diameter mechanical mitral valve;1 case used 29 mm diameter mechanical mitral valve.Intensive care unit stay time was 21.0(20.0,107.0)h;ventilator mechanical ventilation time was 18.0 (16.5,42.5) h.There was no renal failure,re-exploration for hemorrhage and mediastinal infection.All patients were followed up for 56.0 (5.5,63.5) months;1 case suffered sudden death due to malignant arrhythmia;the 5-year survival rate was 78.0％.Conclusion Bentall + MVR shows good short-to-midterm results in treatment of aortic root aneurysm complicated with mitral valve disease in children with Marfan's syndrome;the prosthetic valve and graft size in children are similar to those in adults.
Keywords：Marfan's syndromeAortic root aneurysmMitral insufficiency
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 688-691 )