Effects of different ventilatory modes on weaning from mechanical ventilation after congenital heart disease surgery in infants
Wei Dan
Luo Yi
Ren Xiaoxu
Wu Tao
Qin Guangning
Qu Xinpeng
Wang Shuangxing
Yang Xiang
Ma Zeming
Zhang Hui
Abstract：Objective To analyze the effects of synchronized intermittent mandatory ventilation(pressure-regulated volume-controlled ventilation) combined with pressure support [SIMV (PRVC) + PS] and pressure support/continuous positive airway pressure ventilation(PS/CPAP) on weaning from mechanical ventilation after congenital heart disease surgery in infants.Methods Fifty-eight children(1-6 months old) with left-to-right shunt congenital heart disease undergoing biventricular repair from September 2016 to May 2017 in Capital Institute of Pediatrics were enrolled.All children had SIMV (PRVC) + PS after surgery.With stable hemodynamics and spontaneous respiration,the children were randomly allocated to have SIMV (PRVC) + PS (group A,n =29) PS/ CPAP(group B,n =29) weaning from respiratory support.Weaning time,hemodynamic indicators,spontaneous respiratory indicators,arterial partial pressure of oxygen (PaO2),arterial partial pressure of carbon dioxide (PaCO2) and the success rate of weaning were analyzed.Results Weaning time in group B was significantly shorter than that in group A [(71 ± 55) min vs (112 ± 59) min] (P ＜ 0.05).There were no significant differences of heart rate,systolic blood pressure,respiratory rate,PaO2 and PaCO2 between groups(P ＞0.05).The success rate of weaning was 100％ in both groups.Conclusion PS/CPAP is better than SIMV (PRVC) + PS with a shorter weaning time and stable respiratory and hemodynamic status during weaning period in infants with congenital heart disease surgery.
Keywords：Congenital heart diseaseMechanical ventilationWeaning
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 684-687 )