A hemostatic and antiplatelet pharmacotherapeutic scheme analysis of non-ST-segment elevation acute coronary syndrome with gastrointestinal bleeding
Huang Yonghua
Meng Min
Yang Yong
Abstract：Objective To analyze the effect of hemostatic and antiplatelet treatment on non-ST-segment elevation acute coronary syndrome (ACS) complicated with gastrointestinal bleeding.Methods One non-ST-elevation ACS patient with gastrointestinal bleeding who was admitted in Meishan Hospital of Traditional Chinese Medicine on March 18,2017 was analyzed.The patient was treated by hemostatic and antiplatelet drugs,the therapeutic scheme was evaluated by clinical pharmacists and adjusted according to the condition of patient.Results Drug therapeutic schemes suggested by pharmacists were as follows:①Discontinue anticoagulants and avoid hemostatic drugs such as tranexamic acid and tranexamic acid that have effects on blood coagulation factors;avoid vasoconstrictor pituitrin and phentolamine.②Carbazochrome sodium sulfonate,sodium nitroprussiate and somatostatin should be used.③Low molecular heparin should be used when gastrointestinal bleeding was alleviated.The patient was improved and discharged on April 13th.Conclusion Clinical pharmacists should evaluate the benefit/risk ratio of pharmacotherapeutic scheme and optimize the timing of administration to improve safety and effectiveness of medication for diseases with drug contradiction.
Keywords：Acute coronary syndromeHemostaticsAntiplateletsPharmaceutical care
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 525-529 )