The value of the SYNTAX score in therapeutic effect and prognosis prediction of percutaneous coronary intervention in patients with coronary atherosclerotic heart disease

Cao Jiandong; Ma Xiaofeng; Deng Yong

doi:10.3760/cma.j.issn.1673-4777.2018.04.009

Abstract：Objective To analyze the value of the SYNTAX score in therapeutic effect and prognosis prediction of percutaneous coronary intervention (PCI) in patients with coronary atherosclerotic heart disease (CHD).Methods A total of 130 CHD patients admitted in Qinghai Provincial Cardio-Cerebrovascular Disease Hospital from February 2015 to August 2016 were divided into 3 groups according to the SYNTAX score after PCI:group A (SYNTAX score ＞ 32,n =42),group B (SYNTAX score 23-32,n =43) and group C (SYNTAX score ＜23,n =45).Clinical efficiency and prognosis were analyzed among groups.Results There were no significant differences of left ventricular ejection fraction,left ventricular end-diastolic diameter and cardiac output among 3 groups before treatment (P ＞ 0.05).Twelve months after treatment,left ventricular ejection fraction,left ventricular end-diastolic diameter and cardiac output in group C were significantly higher than those in group A and B[(68.4±3.4)％ vs (63.8 ±3.5)％,(64.3 ±2.7)％;(62.6±1.2)mmvs (46.1 ±3.4),(48.2±3.3)mm;(5.5 ± 0.4) L vs (4.6 ± 0.3),(5.0 ± 0.9) L] (P ＜ 0.05).During 12 months after treatment,incidence of cardio-cerebrovascular adverse events in group C was significantly lower than that in group A and B[4.4％ (2/45) vs 28.6％ (12/42),20.9 ％ (9/43)] (P ＜ 0.05);hospitalization times in group C were significantly less than those in group A and B[(0.52 ±0.12) times/year vs (1.81 ±0.22),(1.21 ±0.12) times/year];length of hospitalization time in group C was significantly shorter than that in group A and B [(7.0 ± 1.0) d vs (9.8 ± 1.2),(8.4 ±1.3) d] (P ＜ 0.05).Conclusion Low SYNTAX score after PCI suggests optimistic therapeutic response and prognosis in CHD patients.