Application value of magnetic-controlled capsule endoscopy in diagnosis of gastric and small intestinal mucosal injuries in patients taking enteric-coated aspirin
Gao Feng
Zhang Jie
Lang Haibo
Shi Jin
Chen Xue
Yan Zhen
Sun Yue
Abstract：Objective To investigate the application value of magnetic-controlled capsule endoscopy in diagnosis of gastric and small intestinal mucosal injuries in patients taking enteric-coated aspirin.Methods Fifteen patients who had taken enteric-coated aspirin without gastrointestinal symptom for more than 3 months and 20 healthy volunteers were enrolled from September to November 2017 in Beijing Anzhen Hospital,Capital Medical University to have magnetic-controlled capsule endoscopy.The Lanza score of gastric and small intestinal mucosal injuries,time indexes of endoscopy,excretion rate and tolerance of magnetic-controlled capsule were analyzed.Results The Lanza scores of gastric and small intestinal mucosa injuries in patients taking aspirin were significantly higher than those in healthy people[4(3,4) points vs 1 (0,2) points,1 (1,2) points vs 0(0,0)points] (P ＜0.05).There was no significant differences of gastric examination time,small intestinal passing time and capsule excretion time between groups(P ＞ 0.05).All of 35 subjects successfully completed magnetic-controlled capsule endoscopy,and the capsule excretion rate was 100％.Most of them excreted the capsule in 20-48 h;1 case excreted the capsule in 120 h.Thirty-three(94.3％) of them were fully tolerated by magnetic-controlled capsule endoscopy;2 cases had mild discomforts which were relieved in 24 h.Conclusions Patients taking enteric-coated aspirin without gastrointestinal symptom may suffer from more gastric and small intestinal mucosal injuries than healthy people.Noninvasive magnetic-controlled capsule endoscopy can be used for real time observation of gastric and small intestinal mucous injuries in patients taking aspirin.
Keywords：Gastric mucous injurySmall intestinal mucous injuryMagnetic-controlled capsule endoscopyEnteric-coated aspirin
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 400-403 )