Vaginal microbiological analysis of mixed vaginal infection
Duan Wenbing
Liu Yun
Ju Ying
Liu Yiqing
Zhang Lulu
Li Xiaoying
Zhao Wanhui
Zhang Bingchang
Abstract：Objective To analyze the microbiological characteristics of mixed vaginal infection.Methods A total of 1 106 cases of gynecological inflammation were enrolled from June to December 2016 in Provincial Hospital Affiliated to Shandong University.Vaginal secretions were separated from these patients.Vaginal cleanness,aerobic vaginitis (AV) score and Nugent score were assessed by phase-contrast microscopy and Gram staining.Results There were 694 cases (62.8％) of single infection and 412 cases (37.2％) of mixed infection.Vaginal cleanliness,pH value,flora density and diversity,hydrogen peroxide,leukocyte esterase,neuraminidase and AV score showed significant differences between single infection and mixed infection patients (x2 =255.44,45.77,28.21,188.05,17.00,19.78,85.43,46.00;all P ＜0.01).AV accounted for 42.6％ (296/694) in patients with single infection,and it accounted for 98.1％ (404/412) in patients with mixed infection.In single AV patients,67.6％ (200/296) patients were suspected of having bacterial vaginosis (BV).In mixed AV patients,AV + BV accounted for 40.6％ (164/404),AV ± candidiasis accounted for 35.6％ (144/404).The severity of AV showed a significant differences between mixed AV and single AV patients[mild AV:50.2％ (203/404) vs 67.2 ％ (199/296),moderate AV:31.2％ (126/404) vs 26.7 ％ (79/296),severe AV:18.6％ (75/404) vs6.1％(18/296)] (x2 =20.15,P ＜0.01).Conclusion There is a high rate of AV infection in female mixed vaginal infection.
Keywords：Vaginal infectionMicroecologyvaginalAerobic vaginitis
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 257-261 )