Relation between copeptin and adverse events after percutaneous coronary intervention in patients with acute coronary syndrome
Peng Ruijun
Liang Xi
Yang Xili
Abstract：Objective To investigate the relation between copeptin and adverse events after percutaneous coronary intervention(PCI) in patients with acute coronary syndrome (ACS).Methods A total of 188 patients with ACS undergoing PCI from July 2015 to July 2016 in Foshan First People's Hospital,Guangdong Province were enrolled.Plasma level of copeptin was tested after admission and the patients were divided into 4 groups according to the quartiles of copeptin level:Q1 group(13.00-16.00 pmol/L,31 cases),Q2 group(17.00-19.00 pmol/L,52 cases),Q3 group(20.00-22.00 pmol/L,70 cases),Q4 group(23.00-25.00 pmol/L,35 cases).Adverse events were recorded in 12 months follow-up.Results Adverse endpoint events occurred in 15 patients(8.0％);173 patients had no endpoint events.Hypertension,diabetes and smoking were significantly related to the occurrence of endpoint events (P ＜ 0.05).Length of operation,number of stents and grade of heart function had significant influenees on the occurrence of endpoint events(P ＜ 0.05).Incidence of endpoint events in Q4 group was significantly higher than that in Q1,Q2,Q3 group[25.7％ (9/31) vs 3.2％ (1/35),1.9％ (1/70),5.7％ (4/52)] (P ＜0.05).Conclusions Basic diseases and surgical procedure are closely related to the occurrence of endpoint events in ACS patients after PCI.Incidence of endpoint events increases with the level of plasma copeptin.
Keywords：Acute coronary syndromeCopeptinPercutaneous coronary intervention
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 27-30 )