Effect of intravascular ultrasound-guided interventional therapy on coronary bifurcation and ostial lesions in patients with non-ST-segment elevation acute coronary syndrome
Qi Shuying
Li Hong
Li Xiang
Zhu Huagang
Jia Ruofei
Meng Shuai
Jin Zening
Abstract：Objective To investigate the effect and long-outcomes of intravenous ultrasound (IVUS)-guided interventional therapy on coronary bifurcation and ostial lesions in patients with non-ST-segment elevation acute coronary syndrome.Methods A total of 106 patients with coronary bifurcation or ostial lesions who were diagnosed by coronary angiography (CAG) and undergoing percutaneous coronary intervention (PCI) in Beijing Anzhen Hospital,Capital Medical University from April 2014 to April 2015 were randomly divided into IVUS group (52 cases) and CAG group(54 cases).Patients in IVUS group had IVUS examination before and after PCI,and interventional procedures and coronary stent selection were based on information provided by IVUS.Patients in CAG group were performed PCI based on CAG results.Characteristics of coronary lesion,number,length and diameter of stent and occurrence of postoperative 12 months major adverse cardiovascular events(MACE,including cardiac death,target vessel revascularization and nonfatal myocardial infarction) were analyzed.Results There were no significant differences of coronary lesion site,number of diseased vessel,number and length of stent between groups (P ＞ 0.05).Diameter of stent in IVUS group was significantly longer than that in CAG group [(3.14 ± 0.42) mm vs (2.87 ± 0.29) mm] (P ＜ 0.05).One case of MACE (1.9％,target vessel revascularization) occurred in IVUS group,and 3 cases of MACE (5.6％,2 cases of target vessel revascularization and 1 case of nonfatal myocardial infarction) occurred in CAG group during 12 months after PCI.Conclusion IVUS-guided PCI can help optimize stent placement and improve long-term prognosis in treating coronary bifurcation and ostial lesions in patients with non-ST-segment elevation acute coronary syndrome.
Keywords：Coronary bifurcation lesionCoronary ostial lesionIntravascular ultrasonography
Publication Date：2018-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 10-13 )