Application of "3 + 1" combined echocardiographic views in prenatal screening of complex congenital heart disease
Zhang Yahui
Jin Mei
Ding Wenhong
Yang Jing
Mo Ying
Ye Wenqian
Lyu Zhenyu
Wang Zhiyuan
Huo Yufeng
Shi Shi
Abstract：Objective To evaluate the value of "3 + 1" combined echocardiographic views (four-chamber view,left and right ventricular outflow tracts view,three-vessel view) in prenatal screening of complex congenital heart disease.Methods Totally 43 127 fetuses who had congenital heart disease screening before birth by "3 + 1" combined echocardiographic view from January 2007 to October 2015 were enrolled through the congenital heart disease screening,treatment and monitoring network in Beijing.Echocardiographic results and autopsy results of induced abortion were analyzed.Results In 43 127 fetuses,413 cases of congenital heart disease were screened by "3 + 1" combined echocardiographic view including 252 cases of complex congenital heart disease;266 cases of congenital heart disease were confirmed by echocardiography after birth or autopsy;there were 6 cases of prenatal misdiagnosis and 14 cases of missed diagnosis.The sensitivity and specificity of " 3 + 1 " combined echocardiographic view in diagnosis of fetal complex congenital heart disease were 94.7％ and 100.0％ respectively.Conclusion The "3 + 1" combined echocardiographic views has a high value in diagnosis of fetal complex congenital heart disease.
Keywords：Congenital heart diseaseFetal echocardiographyFour-chamber viewLeft and right ventricular outflow tracts viewThree-vessel view
Publication Date：2017-12-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1782-1785 )