Predictive value of easy-to-use clinical indicators on early efficacy of adult community-acquired pneumonia
Ju Xuegui
Zhang Wei
Sun Jian
Zeng Qianglin
Abstract：Objective To explore the predictive value of easy-to-use clinical indicators on early efficacy of adult community-acquired pneumonia (CAP).Methods Clinical data of 230 adult patients with CAP from December 2012 to December 2014 in Affiliated Hospital of Chengdu University were analyzed retrospectively.All patients had anti-infective agents,oxygen inhalation,atomization,fluid infusion and supportive therapies.Patients who achieved stable stage after treatment were grouped as stable group;other patients (including dead cases in 72 h after admission) were grouped as unstable group.General data and easy-to-use clinical indicators were analyzed.Results There were 194 cases in stable group and 36 cases in unstable group.Ratios of male,disease time≥3 d and smoking had no significant differences between groups (P ＞ 0.05);ratio of age ＞ 65 years old in stable group was significantly lower than that in unstable group (P ＜ 0.05).With correction of age,ratios of pH ＜ 7.35 and urea nitrogen ＞ 7 mmol/L in stable group were significantly lower than those in unstable group[8.8％ (17/194) vs 27.8％ (10/36),16.5％ (32/194) vs 44.4％ (16/36)] (P ＜ 0.05).There were no significant differences of ratios of artcrial oxygen partial pressure ＜ 60 mmHg,white blood cell count ＜ 4 × 109/L or ＞ 20 × 109/L,hemoglobin＜90 g/L,hematocrit ＜ 30％,platelet count ＜ 100 × 109/L,albumin ＜ 25 g/L,serum sodium ＜130 mmol/L and blood glucose ＞ 13.9 mmol/L between groups(P ＞0.05).Conclusion The pH value and trrea nitrogen level are risk factors of early clinical stability of CAP;pH ＜ 7.35 and urea nitrogen ＞ 7 mmol/L suggest poor early clinical outcomes.
Keywords：PneumoniaClinical easy-to-useLaboratory indexes
Publication Date：2017-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：3( 1636-1638 )