Effect of perioperative use of antibacterials interfered by clinical pharmacist on permanent heart pacemaker implantation
Bai Ying
Wang Jiawei
Abstract：Objective To evaluate the effect of perioperative use of antibacterials intervented by clinical pharmacist on permanent heart pacemaker implantation.Methods Totally 110 patients who had permanent heart pacemaker implantation from June 2015 to May 2016 in Beijing Tongren Hospital,Capital Medical University were enrolled;53 patients had perioperative use of antibacterials intervented by clinical pharmacist(observation group);57 patients were grouped as control group.Clinical effects of perioperative use of antibacterials were analyzed.Results Use rates of cefuroxime and clindamycin in observation group were significantly higher than those in control group[88.7％ (47/53) vs 70.2％ (40/57),9.4％ (5/53) vs 0.0％ (0/57)];cefoxitin use rate in observation group was significantly lower than that in control group [0.0％ (0/53) vs 17.5％ (10/57)] (P ＜ 0.05).Rational rates of drug choice,administration time,medication course and preventive medication in observation group were significantly higher than those in control group [98.1％ (52/53) vs 70.2％ (40/57),100.0％ (53/53) vs 87.7％ (50/57),56.6％ (30/53) vs 22.8％ (13/57),52.8％ (28/53) vs 14.0％ (8/57)] (P ＜ 0.05).The medication course in observation group was significantly shorter than that in control group [(2.3 ± 0.8)d vs (3.0 ± 0.6) d] (P ＜ 0.001).Conclusion Clinical pharmacist intervention helps improve rational use of antibacterials in patients with permanent heart pacemaker implantation.
Keywords：Pacemaker,artificialAntimicrobial agentClinical pharmacist
Publication Date：2017-11-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1624-1627 )