Clinical effect of combined bronchoscopic interventional treatments on malignant carina disease
Miao Weiwei
Wu Xue
Ma Liang
Jiang Lixue
Abstract：Objective To investigate the clinical effect of combined bronchoscopic interventional treatments on malignant carina disease.Methods Totally 27 patients with malignant carina disease who had interventional therapy from January 2010 to December 2016 in Harbin the First Hospital were retrospectively analyzed.All patients had more than 2 kinds of interventional treatments,including high frequency electric knife,cryotherapy,argon plasma coagulation (APC) and stent implantation.Score of the Karnofsky Performance Status(KPS) and the American Thoracic Society(ATS) classification of polypnea were evaluated before and after treatment.Short-term therapeutic effect and occurrences of complications were analyzed.Results In 27 patients,25 patients had high frequency electric knife + cryotherapy + APC;2 patients had high frequency electric knife + cryotherapy + APC +stent implantation.All patients had 42 times of electric knife,48 times of cryotherapy and 32 times of APC;2 stents were implanted.Score of KPS significantly increased and the ATS polypnea grade significantly decreased after treatment compared to those before treatment [(76 ± 11) points vs (55 ± 10) points,(0.7 ± 0.6) vs (3.1 ±0.8)] (P ＜ 0.01).The short-term effective rate was 100％.No severe complication was observed during perioperative period.Conclusion Combined application of high frequency electric knife,cryotherapy,APC and stent implantation is safe and effective in treatment of malignant carina disease.
Keywords：Malignant carina lesionsBronchoscopesInterventional therapy
Publication Date：2017-10-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1503-1506 )