Predictive value of cardiac electro-mechanical activity time ratio for in-hospital adverse cardiac events in patients with chronic heart failure

Zhang Jing; Liu Wenxian

doi:10.3760/cma.j.issn.1673-4777.2017.10.005

Abstract：Objective To explore the predictive value of cardiac electro-mechanical activity time ratio (EMAT％) for in-hospital adverse cardiac events in patients with chronic heart failure.Methods Totally 129 patients with chronic heart failure from August 2015 to May 2017 in Beijing Anzhen Hospital,Capital Medical University were divided into adverse cardiac events group (22 cases) and non-adverse cardiac events group (107 cases).Basic data,clinical indexes,cardiac function indexes and medications were recorded.Risk factors of in-hospital adverse cardiac events were analyzed by binomial logistic regression.The predictive value of EMAT％ for in-hospital cardiac adverse events was analyzed by the receiver operating characteristic(ROC) curve.Results Heart rate,troponin I,B-type natriuretic peptide and EMAT％ in adverse cardiac events group were significantly higher and left ventricular ejection fraction was significantly lower than those in non-adverse cardiac events group[98 (81,122) times/min vs 82 (72,94) times/min,0.650 (0.060,7.235) μg/L vs 0.070 (0.020,1.710)μg/L,1 037.0(653.5,1 905.5)ng/L vs 565.0(166.0,1010.0)ng/L,(17 ±3)％ vs (13 ±3)％,(32 ± 7)％ vs (38± 8)％] (P ＜ 0.05).The use ratio of β-blockers in adverse cardiac events group was significantly lower than that in non-adverse cardiac events group [36.4％ (8/22) vs 69.2％ (74/107)] (P ＜ 0.05).Logistic regression analysis showed that EMAT％ was an indcpendent risk factor of in-hospital adverse cardiac events (odds ratio =1.488,95 ％ confidence interval:1.204-1.840,P ＜ 0.001).The area under ROC curve of EMAT％ in predicting in-hospital cardiac adverse events was 0.822 (95％ CI:0.728-0.917,P ＜ 0.05);the cut-off value was 13.9％;the sensitivity was 86.4％ and the specificity was 68.2％.Conclusion Elevated EMAT％ may be an independent risk factor of in-hospital adverse cardiac events in patients with chronic heart failure.