Cardiovascular and cerebrovascular events in middle and old age patients suffering from diabetes mellitus complicated with hypertension
Ma Zhigang
Zuo Qingyao
Abstract：Objective To analyze the incidence of cardiovascular and cerebrovascular events in middle and old age patients suffering from diabetes complicated with hypertension.Methods Totally 1 125 middle and old age patients with diabetes and hypertension from January 2010 to December 2014 in Beijing Jishuitan Hospital were enrolled as observation group;they were divided into diabetes group (358 cases),hypertension group (401 cases) and diabetes complicated with hypertension group(366 cases).A total of 376 physical examination people were enrolled as control group.The incidence of cardio-cerebrovascular events and all-cause mortality were analyzed.Results During 5-year follow-up,there were 91 cases of cardio-cerebrovascular events and 35 cases of all-cause death in total.The observation group had 86 cases of cardio-cerebrovascular events and 31 cases of all-cause death.The control group had 5 cases of cardio-cerebrovascular events and 4 cases of all-cause death.Log-rank test showed that incidences of myocardial infarction,cerebral infarction,cerebral hemorrhage,total cardio-cerebrovascular events and the all-cause mortality in observation group were significantly higher than those in control group[2.0％ (23/1 125) vs 0.3％ (1/376),3.7％ (42/1 125) vs 0.8％ (3/376),1.9％ (21/1 125) vs 0.3％(1/376),7.6％ (86/1 125) vs 1.3％(5/376),2.8％ (31/1 125) vs 1.1％ (4/376)](P＜0.05).Incidences of cardio-cerebrovascular events and all-cause mortality in diabetes complicated with hypertension group were significantly higher than those in control group,diabetes group and hypertension group[12.6％ (46/366) vs 1.3％ (5/376),6.7％ (24/358),4.0％ (16/401);4.1％ (15/366) vs 1.1％ (4/376),2.8％ (10/358),1.5％ (6/401)] (P ＜ 0.05).Conclusion Middle and old age patients suffering from diabetes complicated with hypertension have high incidence of cardio-cerebrovascular events and high all-cause mortality;incidences of myocardial infarction and cerebral infarction in patients with diabetes are higher than those in patients with hypertension;the incidence of cerebral hemorrhage in patients with hypertension is higher than that in patients with diabetes.
Keywords：Diabetes mellitusHypertensionCardiovascular diseasesCerebrovascular diseases
Publication Date：2017-01-01
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：4( 1306-1309 )