Values of different risk scores in prediction of in-hospital major bleeding after primary percutaneous coronary intervention treating acute ST-segment elevation myocardial infarction
Zhou Shenghui
Liu Ran
Zheng Wen
Nie Shaoping
Abstract：Objective To assess abilities of CRUSADE,ACTION,and ACUITY-HORIZONS scores in predicting in-hospital major bleeding after primary percutaneous coronary intervention(PPCI) in patients with acute ST-segment elevation myocardial infarction(STEMI).Methods A total of 1 080 patients with acute STEMI who underwent PPCI from November 2014 to January 2016 in Beijing Anzhen Hospital,Capital Medical University were retrospectively analyzed.Scores of CRUSADE,ACTION and ACUITY-HORIZONS were calculated in all patients.In-hospital major bleeding was defined as Bleeding Academic Research Consortium type 3 and type 5.Predictive abilities of CRUSADE,ACTION and ACUITY-HORIZONS were assessed by the Hosmer-Lemeshow goodness of fit test and the receiver operating characteristic curve;values of the area under receiver operating characteristic curve (AUC) were analyzed by the DeLong test.Results The incidence of in-hospital major bleeding was 1.8％ (19/1 080).Scores of CRUSADE,ACTION and ACUITY-HORIZONS showed optimistic goodness=of-fit in Hosmer-Lemeshow test (P ＞ 0.05);the AUC values were 0.906,0.909 and 0.747,respectively.In transradial and transfemoral PCI subgroups,3 kinds of risk scores had good Hosmer-Lemeshow goodness-of-fit (P ＞ 0.05);.the AUC values were 0.915,0.896,0.805 in transradial PCI subgroup and 0.864,0.899,0.678 in transfemoral PCI subgroup,respectively.In transradial PCI subgroup and transfemoral PCI subgroups,AUC showed no significant difference between CRUSADE and ACTION (P ＞ 0.05);AUC values of CRUSADE and ACTION were significantly superior to the AUC value of ACUITY-HORIZONS (P ＜ 0.05).Conclusion CRUSADE and ACTION can equally predict in-hospital major bleeding in STEMI patients after PPCI and their predictive ability is superior to that of ACUITY-HORIZONS.
Keywords：Acute ST-segment elevation myocardial infarctionPrimary percutaneous coronary interventionRisk scoreMajor bleeding
Publication Date：2017-09-30
Online Publishing Date：2026-09-14(First online date of this platform, not the publication date of the document)
Pages：5( 1281-1285 )